In vitro and in vivo investigation of the antibacterial, antivirulence, and antiquorum sensing activities of β-carotene against difficult-to-treat resistant Pseudomonas aeruginosa

In vitro and in vivo investigation of the antibacterial, antivirulence, and antiquorum sensing activities of β-carotene against difficult-to-treat resistant Pseudomonas aeruginosa

Abstract Background Difficult-to-treat resistant (DTR) Pseudomonas aeruginosa has strong drug resistance and can tolerate a diversity of antibiotics. Infections triggered by DTR P. aeruginosa urgently require research and development of innovative antibiotics. β-Carotene is a carotenoid pigment with...

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Bibliographic Details
Main Authors: Khaled B. Al-Monofy, Ahmed A. Abdelaziz, Amal M. Abo-Kamar, Lamiaa A. Al-Madboly, Mahmoud H. Farghali
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Microbiology
Subjects:
DTR P. aeruginosa
Antipseudomonal
β-Carotene
Antivirulence
Antibiofilm
Quorum sensing
Online Access:https://doi.org/10.1186/s12866-025-04234-7
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