Diabetes, TZDs, and Bone: A Review of the Clinical Evidence

Evidence from rodent and in vitro models suggests that activation of PPAR-γ by thiazolidinediones (TZDs) causes increased bone marrow adiposity and decreased osteoblastogenesis, resulting in bone loss. TZDs are prescribed for the treatment of diabetes, providing an opportunity to determine whether P...

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Bibliographic Details
Main Author: Ann V. Schwartz
Format: Article
Language:English
Published: Wiley 2006-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/PPAR/2006/24502
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