A Subanesthetic Dose of Isoflurane during Postconditioning Ameliorates Zymosan-Induced Neutrophil Inflammation Lung Injury and Mortality in Mice

A Subanesthetic Dose of Isoflurane during Postconditioning Ameliorates Zymosan-Induced Neutrophil Inflammation Lung Injury and Mortality in Mice

Anesthetic isoflurane (ISO) has immunomodulatory effects. In the present study, we investigated whether a subanesthetic dose of ISO (0.7%) protected against zymosan (ZY) induced inflammatory responses in the murine lung and isolated neutrophils. At 1 and 6 hrs after ZY administration intraperitoneal...

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Main Authors: Hui Wang, Jing Fan, Nan-lin Li, Jun-tang Li, Shi-fang Yuan, Jun Yi, Ling Wang, Jiang-hao Chen, Yong-gang Lv, Qing Yao, Ting Wang, Yu-cai Wang, Rui Ling
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/479628
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http://dx.doi.org/10.1155/2013/479628

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