AI-based body composition analysis of CT data has the potential to predict disease course in patients with multiple myeloma

Abstract The aim of this study was to evaluate the benefit of a volumetric AI-based body composition analysis (BCA) algorithm in multiple myeloma (MM). Therefore, a retrospective monocentric cohort of 91 MM patients was analyzed. The BCA algorithm, powered by a convolutional neural network, quantifi...

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Main Authors: Franz Wegner, Malte Maria Sieren, Hanna Grasshoff, Lennart Berkel, Christoph Rowold, Marcel Philipp Röttgerding, Soleiman Khalil, Sam Mogadas, Felix Nensa, René Hosch, Gabriela Riemekasten, Anna Franziska Hamm, Nikolas von Bubnoff, Jörg Barkhausen, Roman Kloeckner, Cyrus Khandanpour, Theo Leitner
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-11560-3
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