Blood metabolites as mediators in erectile dysfunction: insights from a multi-center proteomics and genetic study

Blood metabolites as mediators in erectile dysfunction: insights from a multi-center proteomics and genetic study

ObjectiveThis study aims to identify circulating proteins causally associated with erectile dysfunction (ED) using Mendelian randomization (MR) analysis.MethodsWe utilized two of the largest multi-center proteomics databases as exposures and the FinnGen database as the outcome source. A large-scale...

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Bibliographic Details
Main Authors: Junhao Chen, Junxian Zhao, Zhi Zhang, Xingcheng Zhu, Jieming Zuo, Zuqing Nie, Yuanzhi Fu, Haifeng Wang, Mengjun Tang, Shi Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
mendelian randomization
proteomics
erectile dysfunction
blood metabolites
precision therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1568780/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1568780/full

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