High-yield spidroin mimics for bioinspired fibers via computational design

The exceptional mechanical properties, biocompatibility, and biodegradability of spider silk make it a promising biomaterial, yet large-scale production remains hindered by challenges in heterologous expression. Existing prokaryotic systems face bottlenecks due to spidroins’ high molecular weight, r...

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Bibliographic Details
Main Authors: Yufan Huang, Junzi Qi, Bingrui An, Bensheng Zhang, Yukang Yang, Cheng Cheng, Bingfang He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1587546/full
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