Impact of early versus conventional kidney replacement therapy initiation in tumor lysis syndrome: a target trial emulation

Impact of early versus conventional kidney replacement therapy initiation in tumor lysis syndrome: a target trial emulation

Abstract Background In the context of tumor lysis syndrome (TLS), the optimal timing and criteria for initiating kidney replacement therapy (KRT) remain unclear. This study aims to assess the effect of initiating KRT at various phosphatemia thresholds on Major Adverse Kidney Events at day 30 (MAKE30...

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Main Authors: Justine Serre, Guillaume Mulier, Charlotte Boud’hors, Marie Lemerle, Moustafa Abdel-Nabey, Corentin Orvain, Anis Chaba, Lucie Biard, Julien Demiselle, Lara Zafrani
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Annals of Intensive Care
Subjects:
Tumor lysis syndrome
Acute kidney injury
Kidney replacement therapy
Online Access:https://doi.org/10.1186/s13613-025-01439-x
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https://doi.org/10.1186/s13613-025-01439-x

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