Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review
Objective Alzheimer’s Disease (AD) is the most common form of dementia, representing a global health challenge. The aim of this review is to assess the impact of different types and intensities of physical exercise on cognitive functions, biomarkers, and the quality of life of AD patients. ...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-01-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/57776 |
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| author | Katarzyna Barabasz Paulina Więcławek Piotr Juda Patrycja Kłaptocz Katarzyna Łukoś-Karcz Dominik Bańkowski Gabriela Pabian Karol Musiał Kamil Bielak |
| author_facet | Katarzyna Barabasz Paulina Więcławek Piotr Juda Patrycja Kłaptocz Katarzyna Łukoś-Karcz Dominik Bańkowski Gabriela Pabian Karol Musiał Kamil Bielak |
| author_sort | Katarzyna Barabasz |
| collection | DOAJ |
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Objective
Alzheimer’s Disease (AD) is the most common form of dementia, representing a global health challenge. The aim of this review is to assess the impact of different types and intensities of physical exercise on cognitive functions, biomarkers, and the quality of life of AD patients.
Methods
Studies from PubMed, Scopus, Cochrane Library, and Web of Science (2000–2024) were analyzed, focusing on the effects of aerobic, resistance, and combined exercises on memory, executive functions, biomarkers (amyloid beta, tau protein, BDNF), daily living abilities (ADL), and quality of life. The review included 42 studies, including randomized controlled trials and meta-analyses.
Results
Moderate-intensity aerobic and combined exercises improve memory and executive functions, while resistance training increases hippocampal volume, supporting spatial memory. High-intensity exercises boost BDNF levels, and moderate-intensity exercises reduce neurodegenerative biomarkers and improve ADL.
Conclusions
Moderate aerobic and combined exercises are effective in preventing and supporting AD therapy. Further research is needed to standardize exercise protocols and evaluate their long-term effects.
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| format | Article |
| id | doaj-art-5c95947ba2f741b1bc7b7bdfb0dc573f |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-5c95947ba2f741b1bc7b7bdfb0dc573f2025-01-28T08:25:02ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2025.37.57776Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature ReviewKatarzyna Barabasz0https://orcid.org/0009-0009-0696-7697Paulina Więcławek1https://orcid.org/0009-0009-3389-0920Piotr Juda2https://orcid.org/0009-0005-0940-3871Patrycja Kłaptocz3https://orcid.org/0009-0001-3324-0321Katarzyna Łukoś-Karcz4https://orcid.org/0009-0004-6690-6507Dominik Bańkowski5https://orcid.org/0009-0008-9439-3103Gabriela Pabian6https://orcid.org/0009-0009-0468-4589Karol Musiał7https://orcid.org/0009-0008-2277-5508Kamil Bielak8https://orcid.org/0009-0002-2280-0116Jagiellonian University Medical College, Świętej Anny 12, 31-008 KrakówJagiellonian University Medical College, Świętej Anny 12, 31-008 KrakówSP ZOZ MSWiA in Kraków, Kronikarza Galla 25, 30-053 KrakówSzpital Wojewódzki w Bielsku-Białej, aleja Armii Krajowej 101, 43-316 Bielsko-BiałaSzpital Wojewódzki w Bielsku-Białej, aleja Armii Krajowej 101, 43-316 Bielsko-BiałaMedical University of Lublin, Aleje Racławickie 1, 20-059 LublinJagiellonian University Medical College, Świętej Anny 12, 31-008 KrakówJagiellonian University Medical College, Świętej Anny 12, 31-008 KrakówMedical University of Lublin, Aleje Racławickie 1, 20-059 Lublin Objective Alzheimer’s Disease (AD) is the most common form of dementia, representing a global health challenge. The aim of this review is to assess the impact of different types and intensities of physical exercise on cognitive functions, biomarkers, and the quality of life of AD patients. Methods Studies from PubMed, Scopus, Cochrane Library, and Web of Science (2000–2024) were analyzed, focusing on the effects of aerobic, resistance, and combined exercises on memory, executive functions, biomarkers (amyloid beta, tau protein, BDNF), daily living abilities (ADL), and quality of life. The review included 42 studies, including randomized controlled trials and meta-analyses. Results Moderate-intensity aerobic and combined exercises improve memory and executive functions, while resistance training increases hippocampal volume, supporting spatial memory. High-intensity exercises boost BDNF levels, and moderate-intensity exercises reduce neurodegenerative biomarkers and improve ADL. Conclusions Moderate aerobic and combined exercises are effective in preventing and supporting AD therapy. Further research is needed to standardize exercise protocols and evaluate their long-term effects. https://apcz.umk.pl/QS/article/view/57776Alzheimer's diseasePhysical activityintensive exercisecognitive functionsbiomarkersBDNF |
| spellingShingle | Katarzyna Barabasz Paulina Więcławek Piotr Juda Patrycja Kłaptocz Katarzyna Łukoś-Karcz Dominik Bańkowski Gabriela Pabian Karol Musiał Kamil Bielak Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review Quality in Sport Alzheimer's disease Physical activity intensive exercise cognitive functions biomarkers BDNF |
| title | Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review |
| title_full | Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review |
| title_fullStr | Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review |
| title_full_unstemmed | Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review |
| title_short | Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review |
| title_sort | assessment of the impact of different types and intensities of physical exercise on the quality of life of patients with alzheimer s disease a literature review |
| topic | Alzheimer's disease Physical activity intensive exercise cognitive functions biomarkers BDNF |
| url | https://apcz.umk.pl/QS/article/view/57776 |
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