Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels

Abstract Although mitochondrial respiration is decreased in most cancer cells, the role of this decrease in carcinogenesis and cancer progression is still unclear. To better understand this phenomenon, instead of further inhibiting mitochondrial function, we induced mitochondrial biogenesis in trans...

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Bibliographic Details
Main Authors: Xiao Wang, Carlos T. Moraes
Format: Article
Language:English
Published: Wiley 2011-10-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1016/j.molonc.2011.07.008
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