Celecoxib-Loaded Electrospun Fibrous Antiadhesion Membranes Reduce COX-2/PGE2 Induced Inflammation and Epidural Fibrosis in a Rat Failed Back Surgery Syndrome Model

To date, failed back surgery syndrome (FBSS) remains a therapy-refractory clinical condition after spinal surgery. The antiadhesion membrane is applied to prevent FBSS by isolating fibrosis; however, the inflammation stimulated by the foreign body and surgical trauma needs to be further resolved sim...

Full description

Saved in:
Bibliographic Details
Main Authors: Wei Wang, Yunhao Wang, Tengfei Lou, Mingqian Ding, Juehong Li, Hao Xiong, Zhixiao Yao, Yingying Ma, Huajiang Chen, Shenghe Liu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2021/6684176
Tags: Add Tag
No Tags, Be the first to tag this record!