Prioritizing attributes of approaches to analyzing patient-centered outcomes that are truncated due to death in critical care clinical trials: a Delphi study

Abstract Background A key challenge for many critical care clinical trials is that some patients will die before their outcome is fully measured. This is referred to as “truncation due to death” and must be accounted for in both the treatment effect definition (i.e. the estimand), as well as the sta...

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Bibliographic Details
Main Authors: Melanie Bahti, Brennan C. Kahan, Fan Li, Michael O. Harhay, Catherine L. Auriemma
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-024-08673-x
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