Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of Atorvastatin
This article presents a highly sensitive electrochemical sensor that utilizes a metal–organic framework (Ag-Fe MOF) to quickly detect and measure Atorvastatin with high sensitivity using the differential pulse voltammetric (DPV) technique. The sensor was developed using a straightforward synthesis t...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Results in Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625000190 |
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| author | Fatemeh Naji Siyahmazgi Karim Asadpour-Zeynali |
| author_facet | Fatemeh Naji Siyahmazgi Karim Asadpour-Zeynali |
| author_sort | Fatemeh Naji Siyahmazgi |
| collection | DOAJ |
| description | This article presents a highly sensitive electrochemical sensor that utilizes a metal–organic framework (Ag-Fe MOF) to quickly detect and measure Atorvastatin with high sensitivity using the differential pulse voltammetric (DPV) technique. The sensor was developed using a straightforward synthesis technique to detect Atorvastatin. The synthesized metal–organic framework was characterized through the use of various analytical techniques, including Fourier-transform infrared spectroscopy (FT-IR), field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX), element map, and electrochemical techniques. The Atorvastatin oxidation calibration graph was plotted using the differential pulse voltammetry technique under the best possible conditions. The calculated detection limit of 0.3 μM and linear ranges of 0.66–40 μM and 40–194.69 μM were found for Atorvastatin oxidation. The findings demonstrate that the sensor that was developed demonstrates favorable repeatability and exceptional stability when used for the determination of Atorvastatin. Notably, one of the significant achievements of this sensor is the ability to determine Atorvastatin in tablets and biological samples. |
| format | Article |
| id | doaj-art-5c0d86b9cd0d41a7827d62445bbe80d1 |
| institution | Kabale University |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-5c0d86b9cd0d41a7827d62445bbe80d12025-01-29T05:01:04ZengElsevierResults in Chemistry2211-71562025-01-0113102036Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of AtorvastatinFatemeh Naji Siyahmazgi0Karim Asadpour-Zeynali1Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz 51666 16471 Tabriz, IranDepartment of Analytical Chemistry, Faculty of Chemistry, University of Tabriz 51666 16471 Tabriz, Iran; Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran; Corresponding author at: Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, 51666 16471 Tabriz, Iran.This article presents a highly sensitive electrochemical sensor that utilizes a metal–organic framework (Ag-Fe MOF) to quickly detect and measure Atorvastatin with high sensitivity using the differential pulse voltammetric (DPV) technique. The sensor was developed using a straightforward synthesis technique to detect Atorvastatin. The synthesized metal–organic framework was characterized through the use of various analytical techniques, including Fourier-transform infrared spectroscopy (FT-IR), field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX), element map, and electrochemical techniques. The Atorvastatin oxidation calibration graph was plotted using the differential pulse voltammetry technique under the best possible conditions. The calculated detection limit of 0.3 μM and linear ranges of 0.66–40 μM and 40–194.69 μM were found for Atorvastatin oxidation. The findings demonstrate that the sensor that was developed demonstrates favorable repeatability and exceptional stability when used for the determination of Atorvastatin. Notably, one of the significant achievements of this sensor is the ability to determine Atorvastatin in tablets and biological samples.http://www.sciencedirect.com/science/article/pii/S2211715625000190Electrochemical SensingAg-Fe based MOFAtorvastatin |
| spellingShingle | Fatemeh Naji Siyahmazgi Karim Asadpour-Zeynali Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of Atorvastatin Results in Chemistry Electrochemical Sensing Ag-Fe based MOF Atorvastatin |
| title | Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of Atorvastatin |
| title_full | Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of Atorvastatin |
| title_fullStr | Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of Atorvastatin |
| title_full_unstemmed | Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of Atorvastatin |
| title_short | Electrochemical sensing platform based on Ag-Fe metal–organic framework for electrocatalytic determination of Atorvastatin |
| title_sort | electrochemical sensing platform based on ag fe metal organic framework for electrocatalytic determination of atorvastatin |
| topic | Electrochemical Sensing Ag-Fe based MOF Atorvastatin |
| url | http://www.sciencedirect.com/science/article/pii/S2211715625000190 |
| work_keys_str_mv | AT fatemehnajisiyahmazgi electrochemicalsensingplatformbasedonagfemetalorganicframeworkforelectrocatalyticdeterminationofatorvastatin AT karimasadpourzeynali electrochemicalsensingplatformbasedonagfemetalorganicframeworkforelectrocatalyticdeterminationofatorvastatin |