EXPERIMENTAL STRATEGY FOR IN VITRO EVALUATION OF CYTOTOXIC / ANTITUMOR PROPERTIES OF NEW METAL COMPLEXES WITH DIFFERENT LIGANDS

EXPERIMENTAL STRATEGY FOR IN VITRO EVALUATION OF CYTOTOXIC / ANTITUMOR PROPERTIES OF NEW METAL COMPLEXES WITH DIFFERENT LIGANDS

PURPOSE. The aim of this study was to evaluate cytotoxic / antitumor properties of newly synthesized metal [Zn(II), Cu(II), Co(II), Ni(II), Zn(II)/Ag(I), Zn(II)/Au(I)] complexes with various ligands (Schiff bases, non-steroidal anti-inflammatory drugs, bile acids) and to introduce an optimized strat...

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Bibliographic Details
Main Authors: R. Alexandrova, R. Spasov, Z. Petrova, T. Zhivkova, L. Dyakova, D. Dinev, M. Glavcheva, B. Andonova-Lilova, A. Abudalleh, M. Georgieva, G. Miloshev, D.-C. Culita, G. Marinescu, V. Alexeeva, C. Podlipnik
Format: Article
Language:English
Published: Trakia University 2019-11-01
Series:Trakia Journal of Sciences
Subjects:
cell cultures
metal compounds
cancer
cytotoxic / anticancer activity
antitumor agents
apoptosis
autophagy
Online Access:http://tru.uni-sz.bg/tsj/Volume%2017,%202019,%20Supplement%202,%20Series%20Biomedical%20Sciences/19_R.Alexandrova.pdf
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http://tru.uni-sz.bg/tsj/Volume%2017,%202019,%20Supplement%202,%20Series%20Biomedical%20Sciences/19_R.Alexandrova.pdf

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