Association of Genomic Alterations with the Presence of Serum Monoclonal Proteins in Chronic Lymphocytic Leukemia

Association of Genomic Alterations with the Presence of Serum Monoclonal Proteins in Chronic Lymphocytic Leukemia

The presence of a monoclonal protein detected by serum immunofixation electrophoresis (sIFE) has been reported as an adverse prognostic factor in chronic lymphocytic leukemia (CLL). However, the genetic underpinning of this finding has not been studied. We retrospectively studied 97 CLL patients wit...

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Main Authors: Juan A. Piñeyroa, Irene López-Oreja, Ferran Nadeu, Ares Martínez-Farran, Juan Ignacio Aróstegui, Mónica López-Guerra, Juan Gonzalo Correa, Aleix Fabregat, Neus Villamor, Ines Monge-Escatín, Nil Albiol, Dolors Costa, Marta Aymerich, Sílvia Beà, Elías Campo, Julio Delgado, Dolors Colomer, Pablo Mozas
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Cells
Subjects:
chronic lymphocytic leukemia
serum monoclonal protein
next-generation sequencing
Online Access:https://www.mdpi.com/2073-4409/13/22/1839
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https://www.mdpi.com/2073-4409/13/22/1839

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