Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage

Objective. To determine if there was an increase in postpartum (PP) hemorrhage after decreasing the PP oxytocin dose from 40 to 30 units. Study Design. Retrospective cohort study comparing 8 months before to 8 months after the change. PP day 1 hemoglobin was subtracted from admission hemoglobin. Me...

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Main Authors: David S. McKenna, Kari Rudinsky, Jiri Sonek
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2014/157625
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author David S. McKenna
Kari Rudinsky
Jiri Sonek
author_facet David S. McKenna
Kari Rudinsky
Jiri Sonek
author_sort David S. McKenna
collection DOAJ
description Objective. To determine if there was an increase in postpartum (PP) hemorrhage after decreasing the PP oxytocin dose from 40 to 30 units. Study Design. Retrospective cohort study comparing 8 months before to 8 months after the change. PP day 1 hemoglobin was subtracted from admission hemoglobin. Mean change was compared by Student’s t-test. The best fit polynomial was analyzed for trends between the two time frames. Women who received blood transfusions were excluded. Results. 73/3564 (2.0%) women received blood transfusions in the pre group and 64/3295 (1.9%) women in the post group, P=0.8. Mean hemoglobin change ± standard deviation was 1.53±0.03 g/dL for pre versus 1.52±0.05 g/dL for post, P=0.68. 1003/3114 (32.2%) in the pre group had a hemoglobin decrease of ≥2 g/dL compared to 918/2895 (31.7%) in the post group, P=0.7. 261/3114 (8.4%) in the pre group had a hemoglobin decrease of ≥3 g/dL compared to 252/2895 (8.7%), P=0.7. There were no significant trends between the two time frames. Conclusion. The change in the dose of PP oxytocin did not result in an increase in postpartum hemorrhage or an increase in the need for blood transfusion.
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spelling doaj-art-5bd71e38794f4f8c82650b3abb92a2402025-02-03T01:03:44ZengWileyJournal of Pregnancy2090-27272090-27352014-01-01201410.1155/2014/157625157625Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum HemorrhageDavid S. McKenna0Kari Rudinsky1Jiri Sonek2Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Miami Valley Hospital, Dayton, OH 45409, USAMaternal-Fetal Medicine, Department of Obstetrics and Gynecology, Miami Valley Hospital, Dayton, OH 45409, USAMaternal-Fetal Medicine, Department of Obstetrics and Gynecology, Miami Valley Hospital, Dayton, OH 45409, USAObjective. To determine if there was an increase in postpartum (PP) hemorrhage after decreasing the PP oxytocin dose from 40 to 30 units. Study Design. Retrospective cohort study comparing 8 months before to 8 months after the change. PP day 1 hemoglobin was subtracted from admission hemoglobin. Mean change was compared by Student’s t-test. The best fit polynomial was analyzed for trends between the two time frames. Women who received blood transfusions were excluded. Results. 73/3564 (2.0%) women received blood transfusions in the pre group and 64/3295 (1.9%) women in the post group, P=0.8. Mean hemoglobin change ± standard deviation was 1.53±0.03 g/dL for pre versus 1.52±0.05 g/dL for post, P=0.68. 1003/3114 (32.2%) in the pre group had a hemoglobin decrease of ≥2 g/dL compared to 918/2895 (31.7%) in the post group, P=0.7. 261/3114 (8.4%) in the pre group had a hemoglobin decrease of ≥3 g/dL compared to 252/2895 (8.7%), P=0.7. There were no significant trends between the two time frames. Conclusion. The change in the dose of PP oxytocin did not result in an increase in postpartum hemorrhage or an increase in the need for blood transfusion.http://dx.doi.org/10.1155/2014/157625
spellingShingle David S. McKenna
Kari Rudinsky
Jiri Sonek
Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage
Journal of Pregnancy
title Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage
title_full Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage
title_fullStr Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage
title_full_unstemmed Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage
title_short Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage
title_sort effects of a new patient safety driven oxytocin dosing protocol on postpartum hemorrhage
url http://dx.doi.org/10.1155/2014/157625
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