An extracellular vesicle based hypothesis for the genesis of the polycystic kidney diseases
Autosomal dominant polycystic kidney (ADPKD) disease is the commonest genetic cause of kidney failure (affecting 1:800 individuals) and is due to heterozygous germline mutations in either of two genes, PKD1 and PKD2. Homozygous germline mutations in PKHD1 are responsible for autosomal recessive poly...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Extracellular Vesicle |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773041724000155 |
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