The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
It has now become universally accepted that hydrogen sulfide (H2S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H2S impacts multiple pathways to exert cytoprotective actions in a number of pathological st...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Scientifica |
| Online Access: | http://dx.doi.org/10.1155/2014/768607 |
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| author | David J. Polhemus John W. Calvert Javed Butler David J. Lefer |
| author_facet | David J. Polhemus John W. Calvert Javed Butler David J. Lefer |
| author_sort | David J. Polhemus |
| collection | DOAJ |
| description | It has now become universally accepted that hydrogen sulfide (H2S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H2S impacts multiple pathways to exert cytoprotective actions in a number of pathological states. This paper will review the recently described cardioprotective actions of hydrogen sulfide in both myocardial ischemia/reperfusion injury and congestive heart failure. |
| format | Article |
| id | doaj-art-5b85b79bc3a84a509b64803e70a91d28 |
| institution | Kabale University |
| issn | 2090-908X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Scientifica |
| spelling | doaj-art-5b85b79bc3a84a509b64803e70a91d282025-02-03T01:01:16ZengWileyScientifica2090-908X2014-01-01201410.1155/2014/768607768607The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart FailureDavid J. Polhemus0John W. Calvert1Javed Butler2David J. Lefer3Department of Pharmacology and Experimental Therapeutics and Cardiovascular Center of Excellence, LSU Health Sciences Center, New Orleans, LA 70112, USADepartment of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USADepartment of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USADepartment of Pharmacology and Experimental Therapeutics and Cardiovascular Center of Excellence, LSU Health Sciences Center, New Orleans, LA 70112, USAIt has now become universally accepted that hydrogen sulfide (H2S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H2S impacts multiple pathways to exert cytoprotective actions in a number of pathological states. This paper will review the recently described cardioprotective actions of hydrogen sulfide in both myocardial ischemia/reperfusion injury and congestive heart failure.http://dx.doi.org/10.1155/2014/768607 |
| spellingShingle | David J. Polhemus John W. Calvert Javed Butler David J. Lefer The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure Scientifica |
| title | The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure |
| title_full | The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure |
| title_fullStr | The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure |
| title_full_unstemmed | The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure |
| title_short | The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure |
| title_sort | cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure |
| url | http://dx.doi.org/10.1155/2014/768607 |
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