The effect of triple CFTR modulator therapy and azithromycin on ion channels and inflammation in cystic fibrosis

Background Inflammation in cystic fibrosis (CF) airways is difficult to treat with well-established regimens often including azithromycin (AZ) as an immunomodulatory drug. As AZ has been reported to require CF transmembrane conductance regulator (CFTR) to be able to reduce interleukin (IL)-8 and giv...

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Bibliographic Details
Main Authors: Suhad Bani Melhim, Lisa E.J. Douglas, James A. Reihill, Damian G. Downey, S. Lorraine Martin
Format: Article
Language:English
Published: European Respiratory Society 2024-12-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/10/6/00502-2024.full
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