R-Loop Formation In Trans at an AGGAG Repeat
Formation of RNA-DNA hybrid, or R-loop, was studied in vitro by transcribing an AGGAG repeat with T7 RNA polymerase. When ribonuclease T1 was present, R-loop formation in cis was diminished, indicating that the transcript was separated from the template and reassociated with it. The transcript was f...
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Main Authors: | Kazuya Toriumi, Takuma Tsukahara, Ryo Hanai |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Journal of Nucleic Acids |
Online Access: | http://dx.doi.org/10.1155/2013/629218 |
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