Protocol for synthesizing both racemic and chiral allenylsilanes through copper-catalyzed silylation of propargyl dichlorides

Summary: Chiral allenylsilanes serve as crucial intermediates in the synthesis of complex pharmaceutical molecules and natural products. Here, we present a protocol for synthesizing both racemic and chiral allenylsilanes through copper-catalyzed silylation of propargyl dichlorides. We describe steps...

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Bibliographic Details
Main Authors: Ying Zhou, Zhengli Liu
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725004289
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