An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells
Interferon (IFN)-γ is a central regulator of cell-mediated immunity in human health and disease, but reduced expression of the target receptors impairs signaling activity and leads to immunotherapy resistance. Although intracellular expression of IFN-γ restores the signaling and downstream functions...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Molecular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmmed.2024.1492370/full |
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