Palladium-catalyzed remote internal C(sp 3)−H bond chlorination of alkenes

Abstract C(sp 3)–Cl bonds are present in numerous biologically active molecules and can also be used as a site for diversification by substitution or cross-coupling reactions. Herein, we report a remote internal site-selective C(sp 3)–H bond chlorination of alkenes through sequential alkene isomeriz...

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Bibliographic Details
Main Authors: Yao-Xin Wang, Zhen Wang, Xiao-Hui Yang
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54896-6
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