The role of m6A regulators mRNA expression in peripheral blood mononuclear cells in chronic hepatitis B: a novel diagnostic and prognostic indicator

The role of m6A regulators mRNA expression in peripheral blood mononuclear cells in chronic hepatitis B: a novel diagnostic and prognostic indicator

Abstract Background Chronic hepatitis B (CHB) is a major health problem worldwide and is a major contributor to the progression of cirrhosis and hepatocellular carcinoma (HCC). Accurate monitoring of the immune response and liver inflammation in CHB patients is critical for effective disease managem...

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Main Authors: Xiu Han, Chengyu Xu, Yahui Song, Xiangwei Wu, Liting Zhou, Tianfeng Wu, Yiling Chen, Lin Wang, Qingzhen Han
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Gastroenterology
Subjects:
Hepatitis B virus (HBV)
RNA m6A methylation (m6A)
Chronic hepatitis B
Peripheral blood mononuclear cells (PBMCs)
METTL3
Online Access:https://doi.org/10.1186/s12876-025-04067-8
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https://doi.org/10.1186/s12876-025-04067-8

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