Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry

Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry

Teratozoospermia, a qualitative sperm disorder characterized by abnormal sperm morphology, represents one of the causes of male infertility worldwide. The metabolic analysis of human seminal plasma (SP), can provide insights into the underlying molecular mechanisms of this condition, identifying nov...

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Main Authors: Serena Correnti, Giuseppina Fanelli, Mariaimmacolata Preianò, Veronica Lelli, Mariagrazia Tarantino, Annalisa Fregola, Massimo Bitonti, Emanuela Chiarella, Anna Maria Timperio, Sara Rinalducci, Rocco Savino, Rosa Terracciano
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
male infertility
human seminal plasma
teratozoospermia
mass spectrometry
metabolomics
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1578998/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2025.1578998/full

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