Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex

Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex

Osteosarcoma is a highly aggressive neoplasm. Traditional platinum chemotherapeutic agents for osteosarcoma inevitably have acquired drug resistance and serious side effects, which have limited their utility. To slow down the reaction of platinum drugs with glutathione (GSH) is a strategy to overcom...

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Bibliographic Details
Main Authors:	Lu Ma, Hua Liu, Yichun Ju, Kai Chen, Yi Yang, Zhichao Zhou, Zhenqin Zhang, Zheng Cai
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2022/3137142
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