Ucp1 Ablation Improves Skeletal Muscle Glycolytic Function in Aging Mice

Ucp1 Ablation Improves Skeletal Muscle Glycolytic Function in Aging Mice

Abstract Muscular atrophy is among the systematic decline in organ functions in aging, while defective thermogenic fat functionality precedes these anomalies. The potential crosstalk between adipose tissue and muscle during aging is poorly understood. In this study, it is showed that UCP1 knockout (...

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Main Authors: Jin Qiu, Yuhan Guo, Xiaozhen Guo, Ziqi Liu, Zixuan Li, Jun Zhang, Yutang Cao, Jiaqi Li, Shuwu Yu, Sainan Xu, Juntong Chen, Dongmei Wang, Jian Yu, Mingwei Guo, Wenhao Zhou, Sainan Wang, Yiwen Wang, Xinran Ma, Cen Xie, Lingyan Xu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
aging
creatine
glycolytic function
skeletal muscle
thermogenic adipose tissue
Online Access:https://doi.org/10.1002/advs.202411015
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https://doi.org/10.1002/advs.202411015

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