Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation

Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation

Abstract Background Pulmonary fibrosis (PF) is an irreversible, progressive, chronic and fatal interstitial lung disease with limited therapeutic options. Dehydrocorydaline (DHC), derived from the traditional Chinese medicinal plant Corydalis yanhusuo, has exhibited a variety of pharmacological prop...

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Bibliographic Details
Main Authors: Jianhan He, Huihui Yue, Shufei Zhang, Ruihan Dong, Fengqin Zhang, Xuewen Wang, Ke Wang, Huilan Zhang, Danlei Yang, Zhaoxing Dong, Huiguo Liu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Respiratory Research
Subjects:
Pulmonary fibrosis
Dehydrocorydaline
Fibroblast
Endoplasmic reticulum stress
Online Access:https://doi.org/10.1186/s12931-025-03218-5
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https://doi.org/10.1186/s12931-025-03218-5

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