Clade IIb Mpox virus (MPXV) vertical transmission and fetal demise in a pregnant rhesus macaque model.

Infection with clade I Mpox virus (MPXV) results in adverse pregnancy outcomes, yet the potential for vertical transmission resulting in fetal harm with clade IIb MPXV, the clade that is currently circulating in the Western Hemisphere, remains unknown. We sought to establish a pregnant rhesus macaqu...

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Main Authors: Nicholas P Krabbe, Ann M Mitzey, Saswati Bhattacharya, Elaina R Razo, Xiankun Zeng, Nell Bekiares, Amy Moy, Amy Kamholz, Julie A Karl, Gregory Daggett, Grace VanSleet, Terry Morgan, Saverio V Capuano, Heather A Simmons, Puja Basu, Andrea M Weiler, David H O'Connor, Thomas C Friedrich, Thaddeus G Golos, Emma L Mohr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320671
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