Chirale Synthesebausteine aus Aminosäuren: Dihydrothiazol-Derivate (Δ4-Thiazoline) aus Cystein

Reaction of cysteine with pivalaldehyde and protection at the nitrogen atom with benzyl chloroformate give the diastereomerically pure cyclic N,S-acetal 2 which is selectively oxidized to the sulfoxide 3. Thiazoline 5 is obtained after oxidative, electrochemically induced decarboxylation and subseq...

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Bibliographic Details
Main Authors: Dieter Seebach, André Jeanguenat, Jürgen Schmidt, Thomas Maetzke
Format: Article
Language:deu
Published: Swiss Chemical Society 1989-10-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9925
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