Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer

Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer

Abstract The human genome encodes 19 adenosine and cytidine deaminase genes, classified as A-to-I versus C-to-U editors. A-to-I editors have been widely identified as a promising therapeutic target in various cancers. Conversely, the investigation into C-to-U editors is relatively limited. This stud...

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Bibliographic Details
Main Authors: Li-Yang Wang, Ji Shi, Mo-Fei Wang, Yi-Meng Liu, Hong-Shan Guo, Jin-Cheng Wang, Shu Jiang, Jia-Qian Liang, Xing-Hua Liao, Shao-Yong Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Prostate cancer
CRPC
RNA-editing
APOBEC3C
Androgen receptor
Online Access:https://doi.org/10.1038/s41598-025-00169-1
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https://doi.org/10.1038/s41598-025-00169-1

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