A comparative analysis of imaging-based algorithms for detecting focal cortical dysplasia type II in children

A comparative analysis of imaging-based algorithms for detecting focal cortical dysplasia type II in children

Abstract Focal cortical dysplasia (FCD) is the leading cause of drug-resistant epilepsy (DRE) in pediatric patients. Accurate detection of FCDs is crucial for successful surgical outcomes, yet remains challenging due to frequently subtle MRI findings, especially in children, whose brain morphology u...

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Main Authors: Jan Šanda, Zuzana Holubová, David Kala, Kateřina Jiránková, Martin Kudr, Tomáš Masák, Anežka Bělohlávková, Pavel Kršek, Jakub Otáhal, Martin Kynčl
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Focal cortical dysplasia type II
Pediatric epilepsy
Cortical thickness
Gray-white matter blurring
Neuroimaging
Online Access:https://doi.org/10.1038/s41598-025-16015-3
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https://doi.org/10.1038/s41598-025-16015-3

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