Cytogenetic finding of simultaneous inversion of chromosome 14 and tetrasomy 8 in a Pediatric B-Lymphoblastic Leukemia-a case report

Abstract Background Clonal cytogenetic abnormalities in B-lymphoblastic leukemia (B-ALL) include structural and numerical chromosomal alterations, where numerical are the most common aberrations. Inversion 14 [inv(14)] is an infrequent finding in B-ALL, but its prognostic and therapeutic significanc...

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Bibliographic Details
Main Authors: Kiran Sachwani, Rehab Pasha, Bushra Kaleem, Neelum Mansoor
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Cytogenetics
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Online Access:https://doi.org/10.1186/s13039-025-00715-6
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