Extracellular vesicles derived from Lactobacillus gasseri GFC-1220 alleviate inflammation via the TLR4/NF-κB signaling pathway in LPS-stimulated RAW264.7 macrophages

Extracellular vesicles derived from Lactobacillus gasseri GFC-1220 alleviate inflammation via the TLR4/NF-κB signaling pathway in LPS-stimulated RAW264.7 macrophages

Abstract Studies on the impact of gram-positive extracellular vesicles have paved the way for novel medical advancements. These vesicles serve as efficient carriers of microbial molecules to target cells, thereby influencing human pathophysiological processes. Thus, this study aimed to investigate t...

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Bibliographic Details
Main Authors: Jin-Ah Koh, Minh Ha Le, Hyo-Jun Lee, Jin-Woo Min, Mi Jung Kim, Hee-Cheol Kang, Yeon-Ju Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Extracellular vesicles
Lactobacillus gasseri GFC-1220
Anti-inflammatory effects
Macrophages
Online Access:https://doi.org/10.1038/s41598-025-99160-z
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https://doi.org/10.1038/s41598-025-99160-z

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