Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report

Collagenous colitis is a clinicopathologic syndrome which presents as chronic, watery, nonbloody diarrhea. Colonic biopsies characteristically show a thick subepithelial collagen band. Barium enema and colonoscopy generally fail to establish the diagnosis. This case report provides evidence for hist...

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Main Author: Franzjosef Schweiger
Format: Article
Language:English
Published: Wiley 1990-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1990/325186
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author Franzjosef Schweiger
author_facet Franzjosef Schweiger
author_sort Franzjosef Schweiger
collection DOAJ
description Collagenous colitis is a clinicopathologic syndrome which presents as chronic, watery, nonbloody diarrhea. Colonic biopsies characteristically show a thick subepithelial collagen band. Barium enema and colonoscopy generally fail to establish the diagnosis. This case report provides evidence for histologic progression over time, pancolonic involvement and the presence of extraintestinal features of collagenous colitis. The reported patient showed no response to 5-aminosalicylic acid. Colonoscopic biopsies in cases of chronic diarrhea can save the patient repeated, uncomfortable and costly investigations.
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institution Kabale University
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spelling doaj-art-586ceebb0b4742c1b39b3aa8a84123942025-02-03T05:59:22ZengWileyCanadian Journal of Gastroenterology0835-79001990-01-0141192210.1155/1990/325186Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case ReportFranzjosef SchweigerCollagenous colitis is a clinicopathologic syndrome which presents as chronic, watery, nonbloody diarrhea. Colonic biopsies characteristically show a thick subepithelial collagen band. Barium enema and colonoscopy generally fail to establish the diagnosis. This case report provides evidence for histologic progression over time, pancolonic involvement and the presence of extraintestinal features of collagenous colitis. The reported patient showed no response to 5-aminosalicylic acid. Colonoscopic biopsies in cases of chronic diarrhea can save the patient repeated, uncomfortable and costly investigations.http://dx.doi.org/10.1155/1990/325186
spellingShingle Franzjosef Schweiger
Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report
Canadian Journal of Gastroenterology
title Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report
title_full Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report
title_fullStr Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report
title_full_unstemmed Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report
title_short Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report
title_sort collagenous colitis histologic progression extraintestinal features and lack of response to 5 asa a case report
url http://dx.doi.org/10.1155/1990/325186
work_keys_str_mv AT franzjosefschweiger collagenouscolitishistologicprogressionextraintestinalfeaturesandlackofresponseto5asaacasereport