The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis

Abstract Background Endothelial cells are integral components of the tumor microenvironment and play a multifaceted role in tumor immunotherapy. Targeting endothelial cells and related signaling pathways can improve the effectiveness of immunotherapy by normalizing tumor blood vessels and promoting...

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Bibliographic Details
Main Authors: Gujun Cong, Jingjing Shao, Feng Xiao, Haixia Zhu, Peipei Kang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Biology Direct
Subjects:
Online Access:https://doi.org/10.1186/s13062-024-00591-x
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