Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A review

Pharmaceutical contaminants, categorized as a subset of Emerging Contaminants, primarily originate from pharmaceutical industries and hospital activities. These pollutants pose significant environmental and public health risks due to their bioactive nature and widespread presence in various ecosyste...

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Main Authors: Pratiwi Wahyu Zuli, Hadiyanto Hadiyanto, Widayat Widayat
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/05/e3sconf_icenis2024_03058.pdf
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author Pratiwi Wahyu Zuli
Hadiyanto Hadiyanto
Widayat Widayat
author_facet Pratiwi Wahyu Zuli
Hadiyanto Hadiyanto
Widayat Widayat
author_sort Pratiwi Wahyu Zuli
collection DOAJ
description Pharmaceutical contaminants, categorized as a subset of Emerging Contaminants, primarily originate from pharmaceutical industries and hospital activities. These pollutants pose significant environmental and public health risks due to their bioactive nature and widespread presence in various ecosystems. Their complex composition in wastewater and low concentrations present a global challenge, as conventional treatment methods often need to be more effective. Advanced oxidation processes (AOPs) have emerged as a promising solution, offering high oxidation efficiency and facilitating the mineralization of such micropollutants. Among various AOPs, ozone-based AOPs stand out because radical hydroxyl is produced with high reactivity. This makes it particularly effective for degrading pharmaceutical micropollutants like antibiotics, which are known for their pseudo-persistent behaviour in the environment. Furthermore, integrating ozone-based AOPs with biological treatments provides a synergistic approach to wastewater treatment, enhancing degradation efficiency while reducing the formation of toxic by-products. This integration can be implemented as a pre-treatment or a post-treatment step, tailoring the process for optimal pollutant removal. This review explores the mechanisms and applications of ozone-based AOPs, focusing on their potential to mitigate pharmaceutical contaminants in wastewater.
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institution Kabale University
issn 2267-1242
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series E3S Web of Conferences
spelling doaj-art-58696dce90a0437b87b2781f448a92012025-02-05T10:49:10ZengEDP SciencesE3S Web of Conferences2267-12422025-01-016050305810.1051/e3sconf/202560503058e3sconf_icenis2024_03058Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A reviewPratiwi Wahyu Zuli0Hadiyanto Hadiyanto1Widayat Widayat2Departement of of Chemical Engineering, Diponegoro UniversityDepartement of of Chemical Engineering, Diponegoro UniversityDepartement of of Chemical Engineering, Diponegoro UniversityPharmaceutical contaminants, categorized as a subset of Emerging Contaminants, primarily originate from pharmaceutical industries and hospital activities. These pollutants pose significant environmental and public health risks due to their bioactive nature and widespread presence in various ecosystems. Their complex composition in wastewater and low concentrations present a global challenge, as conventional treatment methods often need to be more effective. Advanced oxidation processes (AOPs) have emerged as a promising solution, offering high oxidation efficiency and facilitating the mineralization of such micropollutants. Among various AOPs, ozone-based AOPs stand out because radical hydroxyl is produced with high reactivity. This makes it particularly effective for degrading pharmaceutical micropollutants like antibiotics, which are known for their pseudo-persistent behaviour in the environment. Furthermore, integrating ozone-based AOPs with biological treatments provides a synergistic approach to wastewater treatment, enhancing degradation efficiency while reducing the formation of toxic by-products. This integration can be implemented as a pre-treatment or a post-treatment step, tailoring the process for optimal pollutant removal. This review explores the mechanisms and applications of ozone-based AOPs, focusing on their potential to mitigate pharmaceutical contaminants in wastewater.https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/05/e3sconf_icenis2024_03058.pdf
spellingShingle Pratiwi Wahyu Zuli
Hadiyanto Hadiyanto
Widayat Widayat
Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A review
E3S Web of Conferences
title Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A review
title_full Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A review
title_fullStr Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A review
title_full_unstemmed Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A review
title_short Ozone-based Advanced Oxidation Process for pharmaceutical contamination in wastewater: A review
title_sort ozone based advanced oxidation process for pharmaceutical contamination in wastewater a review
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/05/e3sconf_icenis2024_03058.pdf
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AT hadiyantohadiyanto ozonebasedadvancedoxidationprocessforpharmaceuticalcontaminationinwastewaterareview
AT widayatwidayat ozonebasedadvancedoxidationprocessforpharmaceuticalcontaminationinwastewaterareview