Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program
Background: Spinal metastases are the third most common site of metastasis, with around 10% of cancer patients experiencing symptomatic spine involvement. Despite poor overall survival, recent advances in targeted therapies and minimally invasive surgical techniques have made surgery a more viable o...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
|
| Series: | Journal of Craniovertebral Junction and Spine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jcvjs.jcvjs_158_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832087221847457792 |
|---|---|
| author | Salim M. Yakdan Maya Herrera Nour Wehbe Monifa Al Akoum Muhammad Irfan Kaleem Miguel A. Ruiz-Cardozo Karan Joseph Nada Assaf Hani Dimassi |
| author_facet | Salim M. Yakdan Maya Herrera Nour Wehbe Monifa Al Akoum Muhammad Irfan Kaleem Miguel A. Ruiz-Cardozo Karan Joseph Nada Assaf Hani Dimassi |
| author_sort | Salim M. Yakdan |
| collection | DOAJ |
| description | Background:
Spinal metastases are the third most common site of metastasis, with around 10% of cancer patients experiencing symptomatic spine involvement. Despite poor overall survival, recent advances in targeted therapies and minimally invasive surgical techniques have made surgery a more viable option for managing metastatic spine disease.
Objective:
Our study aims to identify perioperative risk factors associated with poor outcomes following spine surgery in the setting of spinal cord metastasis.
Methods:
We used the National Surgical Quality Improvement Program data. Patients with metastatic spine disease undergoing spine surgery were identified. Our primary outcome measure was 30-day morbidity and mortality after surgery. Our secondary outcome was prolonged hospital stay. Logistic regression model for each outcome based on individual characteristics was developed.
Results:
A total of 2109 patients were included. The 30-day morbidity and mortality rates were 19.1%. Significant predictors included smoking, more than 10% body weight loss, surgical urgency, dependent status, and preoperative albumin levels. In addition, 28.6% of patients experienced a prolonged hospital stay, with significant predictors including chemotherapy, surgical urgency, dependent status, preoperative hematocrit, neurological deficits, preoperative albumin levels, and surgical complexity.
Conclusion:
Our study provides valuable insights into the risk factors associated with mortality, morbidity, and prolonged hospital stay in patients with spinal cord metastasis undergoing spine surgery. These identified factors can be instrumental in assisting clinicians with risk stratification, preoperative optimization, and postoperative care planning, ultimately improving patient outcomes. Further research and validation of these predictive models are warranted to ensure their generalizability and applicability in clinical practice. |
| format | Article |
| id | doaj-art-586920489b7945ceb10e8ca268592aa6 |
| institution | Kabale University |
| issn | 0974-8237 0976-9285 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Craniovertebral Junction and Spine |
| spelling | doaj-art-586920489b7945ceb10e8ca268592aa62025-02-06T06:11:06ZengWolters Kluwer Medknow PublicationsJournal of Craniovertebral Junction and Spine0974-82370976-92852024-12-0115449950510.4103/jcvjs.jcvjs_158_24Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement ProgramSalim M. YakdanMaya HerreraNour WehbeMonifa Al AkoumMuhammad Irfan KaleemMiguel A. Ruiz-CardozoKaran JosephNada AssafHani DimassiBackground: Spinal metastases are the third most common site of metastasis, with around 10% of cancer patients experiencing symptomatic spine involvement. Despite poor overall survival, recent advances in targeted therapies and minimally invasive surgical techniques have made surgery a more viable option for managing metastatic spine disease. Objective: Our study aims to identify perioperative risk factors associated with poor outcomes following spine surgery in the setting of spinal cord metastasis. Methods: We used the National Surgical Quality Improvement Program data. Patients with metastatic spine disease undergoing spine surgery were identified. Our primary outcome measure was 30-day morbidity and mortality after surgery. Our secondary outcome was prolonged hospital stay. Logistic regression model for each outcome based on individual characteristics was developed. Results: A total of 2109 patients were included. The 30-day morbidity and mortality rates were 19.1%. Significant predictors included smoking, more than 10% body weight loss, surgical urgency, dependent status, and preoperative albumin levels. In addition, 28.6% of patients experienced a prolonged hospital stay, with significant predictors including chemotherapy, surgical urgency, dependent status, preoperative hematocrit, neurological deficits, preoperative albumin levels, and surgical complexity. Conclusion: Our study provides valuable insights into the risk factors associated with mortality, morbidity, and prolonged hospital stay in patients with spinal cord metastasis undergoing spine surgery. These identified factors can be instrumental in assisting clinicians with risk stratification, preoperative optimization, and postoperative care planning, ultimately improving patient outcomes. Further research and validation of these predictive models are warranted to ensure their generalizability and applicability in clinical practice.https://journals.lww.com/10.4103/jcvjs.jcvjs_158_24metastasismorbiditymortalityoncologyoutcomesspine surgery |
| spellingShingle | Salim M. Yakdan Maya Herrera Nour Wehbe Monifa Al Akoum Muhammad Irfan Kaleem Miguel A. Ruiz-Cardozo Karan Joseph Nada Assaf Hani Dimassi Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program Journal of Craniovertebral Junction and Spine metastasis morbidity mortality oncology outcomes spine surgery |
| title | Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program |
| title_full | Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program |
| title_fullStr | Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program |
| title_full_unstemmed | Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program |
| title_short | Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program |
| title_sort | outcome of spine surgery in the context of spinal metastatic disease the national surgical quality improvement program |
| topic | metastasis morbidity mortality oncology outcomes spine surgery |
| url | https://journals.lww.com/10.4103/jcvjs.jcvjs_158_24 |
| work_keys_str_mv | AT salimmyakdan outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT mayaherrera outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT nourwehbe outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT monifaalakoum outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT muhammadirfankaleem outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT miguelaruizcardozo outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT karanjoseph outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT nadaassaf outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram AT hanidimassi outcomeofspinesurgeryinthecontextofspinalmetastaticdiseasethenationalsurgicalqualityimprovementprogram |