WNT3 promotes chemoresistance to oxaliplatin in oral squamous cell carcinoma via regulating ABCG2 expression

WNT3 promotes chemoresistance to oxaliplatin in oral squamous cell carcinoma via regulating ABCG2 expression

Abstract Oxaliplatin (OXA) is a frontline therapeutic agent used in the treatment of oral squamous cell carcinoma (OSCC). However, the development of chemoresistance has emerged as a significant challenge, compromising the effectiveness of treatment strategies. Therefore, there is a critical need to...

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Bibliographic Details
Main Authors: Kairui Sun, Xuyang Zhang, Ruihuan Gan, Shuoqi Lin, Yu Chen, Dali Zheng, Youguang Lu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell & Bioscience
Subjects:
Oral squamous cell carcinoma
Chemoresistance
ABC transporters
WNT canonical signaling pathway
Oxaliplatin
Online Access:https://doi.org/10.1186/s13578-025-01414-w
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https://doi.org/10.1186/s13578-025-01414-w

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