Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis

Introduction Approximately 60 million individuals worldwide used opioids in 2021, constituting 1.2% of the global adult population. This study aimed to evaluate the effectiveness of integrated treatment strategies for opioid use disorder and nicotine use disorder by assessing the impact of smoking c...

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Main Authors: Shu-Wua Lee, Po-Chung Yu, Ting-Ting Yen, Chiann-Yi Hsu, Li-Jou Lai, I-Chun Chen, Ting-Gang Chang
Format: Article
Language:English
Published: European Publishing 2024-07-01
Series:Tobacco Induced Diseases
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Online Access:https://www.tobaccoinduceddiseases.org/Impact-of-the-Ottawa-model-on-opiate-screening-and-smoking-cessation-in-methadone,191247,0,2.html
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author Shu-Wua Lee
Po-Chung Yu
Ting-Ting Yen
Chiann-Yi Hsu
Li-Jou Lai
I-Chun Chen
Ting-Gang Chang
author_facet Shu-Wua Lee
Po-Chung Yu
Ting-Ting Yen
Chiann-Yi Hsu
Li-Jou Lai
I-Chun Chen
Ting-Gang Chang
author_sort Shu-Wua Lee
collection DOAJ
description Introduction Approximately 60 million individuals worldwide used opioids in 2021, constituting 1.2% of the global adult population. This study aimed to evaluate the effectiveness of integrated treatment strategies for opioid use disorder and nicotine use disorder by assessing the impact of smoking cessation within a methadone treatment framework. Methods In a retrospective cohort study, 53 methadone maintenance patients were divided into 16 treatment-seeking smokers (TSS) and 37 treatment-rejecting smokers (TRS) based on their participation in the Ottawa model for smoking cessation plus 16 weeks of varenicline treatment. Both groups received standard methadone treatment for 68 weeks. TSS were followed up for 44 weeks to assess smoking cessation outcomes, while TRS had none due to their lack of participation in smoking cessation treatment. Results The median age of the TSS group was 48 years, while that of the TRS group was 45.5 years. Males comprised 75% of TSS and 94.6% of the TRS. TSS exhibited an 83% decrease in positive opioid screen results compared to TRS (p=0.023). In TSS, peak smoking cessation success was observed at week 20, with 57% of participants maintaining carbon monoxide levels <5 ppm. Conclusions The significant reduction in positive opioid screens and the high smoking cessation rate in the TSS group highlight the efficacy of combined treatment methods. This study underscores the advantages of integrating smoking cessation with methadone maintenance treatment, indicating that comprehensive approaches can substantially improve treatment outcomes.
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spelling doaj-art-57f937eb009c4d24a1ba9ae9635c33b42025-01-24T15:27:00ZengEuropean PublishingTobacco Induced Diseases1617-96252024-07-0122July11210.18332/tid/191247191247Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysisShu-Wua Lee0Po-Chung Yu1Ting-Ting Yen2Chiann-Yi Hsu3Li-Jou Lai4I-Chun Chen5Ting-Gang Chang6https://orcid.org/0000-0001-9156-7413Department of Psychiatry, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Psychiatry, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Otorhinolaryngology, Taichung Veterans General Hospital, Taichung, TaiwanBiostatistics Task Force, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Psychiatry, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Psychiatry, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Psychiatry, Taichung Veterans General Hospital, Taichung, TaiwanIntroduction Approximately 60 million individuals worldwide used opioids in 2021, constituting 1.2% of the global adult population. This study aimed to evaluate the effectiveness of integrated treatment strategies for opioid use disorder and nicotine use disorder by assessing the impact of smoking cessation within a methadone treatment framework. Methods In a retrospective cohort study, 53 methadone maintenance patients were divided into 16 treatment-seeking smokers (TSS) and 37 treatment-rejecting smokers (TRS) based on their participation in the Ottawa model for smoking cessation plus 16 weeks of varenicline treatment. Both groups received standard methadone treatment for 68 weeks. TSS were followed up for 44 weeks to assess smoking cessation outcomes, while TRS had none due to their lack of participation in smoking cessation treatment. Results The median age of the TSS group was 48 years, while that of the TRS group was 45.5 years. Males comprised 75% of TSS and 94.6% of the TRS. TSS exhibited an 83% decrease in positive opioid screen results compared to TRS (p=0.023). In TSS, peak smoking cessation success was observed at week 20, with 57% of participants maintaining carbon monoxide levels <5 ppm. Conclusions The significant reduction in positive opioid screens and the high smoking cessation rate in the TSS group highlight the efficacy of combined treatment methods. This study underscores the advantages of integrating smoking cessation with methadone maintenance treatment, indicating that comprehensive approaches can substantially improve treatment outcomes.https://www.tobaccoinduceddiseases.org/Impact-of-the-Ottawa-model-on-opiate-screening-and-smoking-cessation-in-methadone,191247,0,2.htmlsmoking cessationmethadone maintenance treatmentottawa model for smoking cessationurine drug testopioid use disorder
spellingShingle Shu-Wua Lee
Po-Chung Yu
Ting-Ting Yen
Chiann-Yi Hsu
Li-Jou Lai
I-Chun Chen
Ting-Gang Chang
Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis
Tobacco Induced Diseases
smoking cessation
methadone maintenance treatment
ottawa model for smoking cessation
urine drug test
opioid use disorder
title Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis
title_full Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis
title_fullStr Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis
title_full_unstemmed Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis
title_short Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis
title_sort impact of the ottawa model on opiate screening and smoking cessation in methadone treated patients with opioid use disorder a retrospective cohort analysis
topic smoking cessation
methadone maintenance treatment
ottawa model for smoking cessation
urine drug test
opioid use disorder
url https://www.tobaccoinduceddiseases.org/Impact-of-the-Ottawa-model-on-opiate-screening-and-smoking-cessation-in-methadone,191247,0,2.html
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