TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis

Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described. In this study, both in vitro (HPCs cocultured with hepatic stellate cells (HSCs)...

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Bibliographic Details
Main Authors: Ai-Ting Yang, Dou-Dou Hu, Ping Wang, Min Cong, Tian-Hui Liu, Dong Zhang, Ya-Meng Sun, Wen-Shan Zhao, Ji-Dong Jia, Hong You
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/1492694
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