SARS‐CoV‐2 structural coverage map reveals viral protein assembly, mimicry, and hijacking mechanisms

SARS‐CoV‐2 structural coverage map reveals viral protein assembly, mimicry, and hijacking mechanisms

Abstract We modeled 3D structures of all SARS‐CoV‐2 proteins, generating 2,060 models that span 69% of the viral proteome and provide details not available elsewhere. We found that ˜6% of the proteome mimicked human proteins, while ˜7% was implicated in hijacking mechanisms that reverse post‐transla...

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Bibliographic Details
Main Authors: Seán I O’Donoghue, Andrea Schafferhans, Neblina Sikta, Christian Stolte, Sandeep Kaur, Bosco K Ho, Stuart Anderson, James B Procter, Christian Dallago, Nicola Bordin, Matt Adcock, Burkhard Rost
Format: Article
Language:English
Published: Springer Nature 2021-09-01
Series:Molecular Systems Biology
Subjects:
bioinformatics
COVID‐19
data visualization
SARS‐CoV‐2
structural biology
Online Access:https://doi.org/10.15252/msb.202010079
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https://doi.org/10.15252/msb.202010079

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