Comprehensive mathematical modeling of age-dependent oocyte quality and quantity for predicting live birth rate

Comprehensive mathematical modeling of age-dependent oocyte quality and quantity for predicting live birth rate

BackgroundAge-related decline in fertility is widely recognized. However, a quantitative evaluation of changes in oocyte quality and quantity remains insufficient. Therefore, developing a mathematical model to quantitatively predict live birth rates affected by these changes is essential for support...

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Main Authors: Toshio Sujino, Tatsuyuki Ogawa, Akira Komiya, Makiko Tajima, Yuko Takayanagi, Yurie Nako, Hayata Nakajo, Kenichiro Hiraoka, Isao Tamura, Hidetoshi Yamashita, Kiyotaka Kawai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Endocrinology
Subjects:
ovarian aging
fertility decline
anti-Müllerian hormone
live birth rate
prediction
curve fitting
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1595970/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1595970/full

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