Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention

Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention

Erectile dysfunction (ED) is a prevalent condition linked to diabetes and cardiovascular diseases, with conventional treatments often associated with adverse effects. Plant-derived products, though less explored, offer potential alternatives. This study evaluated the inhibitory effect of citrulline...

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Bibliographic Details
Main Authors: Abdulhakeem Olarewaju Sulyman, Olawale Moshood Aliyu, Emmanuel Oladipo Ajani, Yusuf Folohunsho Abdulkareem, Isaac Ade Afe, Fathia Oluwakemi Abdulyakeen, Halimat Yusuf Lukman, Saheed Sabiu, Karishma Singh, Kuben Naidoo
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Scientific African
Subjects:
Erectile dysfunction
Phosphodiesterase type 5
Citrulline
Inhibition kinetics
Molecular dynamics simulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227625000432
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