<i>Alternaria alternata</i> (Fr) Keissl Crude Extract Inhibits HIV Subtypes and Integrase Drug-Resistant Strains at Different Stages of HIV Replication

<i>Alternaria alternata</i> (Fr) Keissl Crude Extract Inhibits HIV Subtypes and Integrase Drug-Resistant Strains at Different Stages of HIV Replication

<b>Background/Objectives</b>: The development of HIV drug resistance to current antiretrovirals, and the antiretrovirals’ inability to cure HIV, provides the need of developing novel drugs that inhibit HIV-1 subtypes and drug-resistance strains. Fungal endophytes, including <i>Alte...

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Bibliographic Details
Main Authors: Darian Naidu, Ernest Oduro-Kwateng, Mahmoud E. S. Soliman, Sizwe I. Ndlovu, Nompumelelo P. Mkhwanazi
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceuticals
Subjects:
<i>A. alternata</i>
anti-HIV activity
molecular docking
integrase inhibitors
HIV-subtypes
Online Access:https://www.mdpi.com/1424-8247/18/2/189
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