Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair

Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair

Abstract In the field of bone tissue engineering, the development of effective strategies for bone defect repair remains a major challenge. Herein, we report a novel approach involving the integration of high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles (3D-sEVs) into a...

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Bibliographic Details
Main Authors: Wenbin Xu, Wenling Gao, Yi Zhang, Gang Hou, Wenhui Zhang, Jintao Deng, Kun Wang, Yichun Xu, Boxun Liu, Tao Xu, Chang Liu, Tangzhao Liang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Subjects:
3D cultured adipose-derived stem cell small extracellular vesicles
Bone repair
Angiogenesis
Hyaluronic acid methacrylate (HAMA)
Calcium phosphate cement (CPC)
Online Access:https://doi.org/10.1186/s12951-025-03596-4
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https://doi.org/10.1186/s12951-025-03596-4

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