Stabilized β-Catenin Ameliorates ALPS-Like Symptoms of B6/lpr Mice
Autoimmune lymphoproliferative syndrome (ALPS) is an incurable disease mainly caused by the defect of Fas-mediated apoptosis and characterized by nonmalignant autoimmune lymphoproliferation. Stabilized β-catenin could not only potentiate Fas-mediated T cell apoptosis via upregulating the expression...
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Main Authors: | Xiaoxie Xu, Jun Huang, Mei Zhao, Huanpeng Chen, Jinhua Mo, Xiaoqing Zhou, Qiao Su, Bolan Yu, Zhaofeng Huang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2017/3469108 |
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