Baseline predictors of antibiotics de-escalation from empirical therapies in an intensive care unit: a five-year retrospective study

Baseline predictors of antibiotics de-escalation from empirical therapies in an intensive care unit: a five-year retrospective study

Abstract Background The alarming rate of bacterial resistance has urged for vigorous antibiotic de-escalation cultures worldwide. However, the art of de-escalation remains challenging as most clinicians have the fear or stigma that antibiotic de-escalation is strongly associated with higher mortalit...

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Bibliographic Details
Main Authors: Ann Lisa Arulappen, Amer Hayat Khan, Monica Danial, Syed Shahzad Hasan, Ting Soo Chow, Nehad Jaser Ahmed, Chiau Ming Long
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Infectious Diseases
Subjects:
Antibiotics
De-escalation
Factors
Mortality
Retrospective analysis
Online Access:https://doi.org/10.1186/s12879-025-10752-6
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https://doi.org/10.1186/s12879-025-10752-6

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