Bioinformatics-based analysis of fatty acid metabolic reprogramming in hepatocellular carcinoma: cellular heterogeneity, therapeutic targets, and drug discovery

Bioinformatics-based analysis of fatty acid metabolic reprogramming in hepatocellular carcinoma: cellular heterogeneity, therapeutic targets, and drug discovery

Fatty acid (FA) reprogramming has a significant role in liver cancer. However, the contribution of FA metabolism reprogramming to the heterogeneity of hepatocellular carcinoma (HCC) has not been established. Bioinformatics analysis using single-cell sequencing, a non-negative matrix factorization (N...

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Main Authors: Yingying Guo, Run Shi, Yu Xu, William C. Cho, Jun Yang, You Yeon Choi, Jing Sun, Yan Ma, Olga Pozharitskaya, Alexander Shikov, Hongliang Li, Minglun Li, Zhenpeng Qiu, Woong Mo Yang, Pierre Duez, Hongxi Xu, Xuanbin Wang
Format: Article
Language:English
Published: Compuscript Ltd 2024-11-01
Series:Acta Materia Medica
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0057
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https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0057

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