Unraveling the mechanisms of propofol-induced psychological dependence: a multi-omics approach linked to gut microbiota in hippocampal function

Unraveling the mechanisms of propofol-induced psychological dependence: a multi-omics approach linked to gut microbiota in hippocampal function

IntroductionDrug abuse is becoming a global public health crisis. According to the United Nations, the number of drug users worldwide has increased dramatically over the past decade, with a surge in the number of drug abusers. The problem was exacerbated by the expanding market for illicit drugs and...

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Bibliographic Details
Main Authors: Li Wang, Tangyi Wang, Yadian Lei, Yudong Su, Yuxin Lin, Zhijing Wu, Qiong Wu, Shoude Zhang, Haiyan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Medicine
Subjects:
propofol
psychiatric dependence
gut microbes
transcriptomics
metabolomics
hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1539467/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1539467/full

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