ACSL4 at the helm of the lipid peroxidation ship: a deep-sea exploration towards ferroptosis

Lipid peroxidation stands as a prominent hallmark and a prerequisite for the onset of ferroptosis. Lipid metabolism holds a pivotal role in regulating this process, forming the metabolic foundation for cellular sensitivity to ferroptosis. Studies in lipid metabolomics reveal that the activation of P...

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Bibliographic Details
Main Authors: Yulang Jiang, Meng Zhang, Mingyu Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1594419/full
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